Fagron Concepts

Fagron Advanced Derma is the revolutionary global standard for advanced skin care. It offers pharmaceutical bases that are formulated according to the latest scientific knowledge
Looking at expanding or starting up compounding in your pharmacy? Fagron can assist you in furnishing your lab in compliance with the Pharmacy Board Compounding Guidelines
SyrSpend® SF is an innovative vehicle range for preparing oral liquid dosage forms. The excellent compatibility with a broad range of medications and meticulous ingredient safety make SyrSpend® SF vital for every compounding pharmacist.

SyrSpend® SF – Scientific evidence for another 10 APIs

Thu, 14/04/2016

SyrSpend® SF is a GMP-produced oral liquid vehicle that is supported by extensive scientific literature. In a study published in the April edition of Die Pharmazie, the physical and chemical stability of 10 APIs (Active Pharmaceutical Ingredients) was studied in SyrSpend® SF PH4 liquid1:

  • Cholecalciferol
  • Haloperidol
  • Imipramine hydrochloride
  • Levodopa/carbidopa
  • Lorazepam
  • Minocycline hydrochloride
  • Tacrolimus monohydrate
  • Terbinafine
  • Tramadol hydrochloride
  • Valsartan

The beyond-use date for almost all studied SyrSpend® SF suspensions is 90 days stored under refrigerated conditions (2-8°C) and at room temperature (20-25°C). Minocycline hydrochloride has a beyond-use date of 60 days at both storage temperatures, levodopa/carbidopa and lorazepam have respectively 30 and 60 days stability at room temperature.

An overview of all available formulations with SyrSpend® SF can be found on our free online formulations database, Compounding Matters.


1Polonini HC, Silva SL, Cunha CN, Brandão MAF, Ferreira AO. Compatibility of cholecalciferol, haloperidol, imipramine hydrochloride, levodopa/carbidopa, lorazepam, minocycline hydrochloride, tacrolimus monohydrate, terbinafine, tramadol hydrochloride and valsartan in SyrSpend® SF PH4 oral suspensions. Die Pharmazie, 71: 185-191 (April 2016).