Fagron Concepts

Fagron Advanced Derma is the revolutionary global standard for advanced skin care. It offers pharmaceutical bases that are formulated according to the latest scientific knowledge
Looking at expanding or starting up compounding in your pharmacy? Fagron can assist you in furnishing your lab in compliance with the Pharmacy Board Compounding Guidelines
SyrSpend™ SF is an innovative vehicle range for preparing oral liquid dosage forms. The excellent compatibility with a broad range of medications and meticulous ingredient safety make SyrSpend™ SF vital for every compounding pharmacist.

SyrSpend® SF PH4 Stability

Fri, 09/06/2017

new peer-reviewed study has been published by the International Journal of Pharmaceutical Compouding highlighting the stability of 10 commonly used active pharmaceutical ingredients in Fagron's SyrSpend® SF PH4 vehicle. SyrSpend® SF PH4 (liquid) is a ready-to-use, all-in-one suspending and sweetening oral liquid vehicle that can be used for compounding and as an administration aid. The product allows for more a convenient method for preparation of suspensions which provides pharmaceutical stability and consistency.

The study investigates the stability of the suspended pharmaceutical ingredients at both controlled refrigeration temperature (2°C to 8°C) and controlled room temperature (20°C to 25°C). The stability of each suspension was verified by high-performance liquid chromotography to measure the quantity of the active pharmaceutical ingredient remaining over a certain period of the time. It was concluded that the suspensions had reached beyond-use-date past 90 days to suggest that SyrSpend® SF PH4 is stable when used with the different pharmacological classes of active pharmaceutical ingredients.

Alprazolam 1 mg/ml in SyrSpend® SF PH4 (liquid)
Atropine sulfate 0.1 mg/ml in SyrSpend® SF PH4 (liquid)
Glutamine 250 mg/ml in SyrSpend® SF PH4 (liquid)
Levofloxacin 50 mg/ml in SyrSpend® SF PH4 (liquid)
Metoprolol tartrate 10 mg/ml in SyrSpend® SF PH4 (liquid)
Nitrofurantoin 2 - 10 mg/ml in SyrSpend® SF PH4 (liquid)
Ondansetron HCl 0.8 mg/ml in SyrSpend® SF PH4 (liquid)
Oxandrolone 3 mg/ml in SyrSpend® SF PH4 (liquid)
Pregabalin 20 mg/ml in SyrSpend® SF PH4 (liquid)
Riboflavin (vit. B2) 10 mg/ml in SyrSpend® SF PH4 (liquid)

Visit our Compounding Matters formulation database for over 200 other oral liquid formulations with our Syrspend® SF vehicles.